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CRM197

Pfenex CRM197 is the first and only commercially available cGMP CRM197 used in a marketed conjugate vaccine

CRM197 is a non-toxic mutant of diphtheria toxin that functions as a carrier protein for polysaccharides and haptens. CRM197 enhances the immunogenicity of antigens in conjugate vaccines.

Scalability

We ensure scientists & manufacturing professionals have access to a continuous supply of research & cGMP grade CRM197, from milligrams to kilograms, throughout development and commercialization.

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Compliance

Pfenex CRM197 is supported by a Drug Master File (DMF) filed with the US FDA Center for Biologics Evaluation and Research (CBER). Access to the DMF simplifies regulatory filings, expediting time to vaccine approval.

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For research use, order CRM197 online in a size that suits your needs. Visit our order page to read more about the product – including source, species, and formulation – and order today.

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