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Meningococcal ACWYX Conjugate Vaccine in 2-to-29-Year-Olds in Mali and Gambia

New England Journal of Medicine
05/25/2023

Cross reacting material (CRM197) as a carrier protein for carbohydrate conjugate vaccines targeted at bacterial and fungal pathogens

PubMed®
07/22/2022

PeliCRM197® Brochure

Ligand logo

Ligand’s Partner Merck Receives FDA Approval for Vaxneuvance™ for the Prevention of Invasive Pneumococcal Disease in Adults Caused by 15 Serotypes

Ligand Pharmaceuticals
07/19/2021
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Merck Vaccine using Ligand CRM197 has BLA Accepted for Review by FDA

Ligand Pharmaceuticals
01/13/2021
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Pfenex Acquired by Ligand Pharmaceuticals

Ligand Pharmaceuticals
10/01/2020
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Ligand Licensee receives Advance Market Commitment award for pneumococcal vaccine supply

PATH
06/18/2020
Pelican Expression Technology logo

Serum Institute of India Private Limited has achieved World Health Organization (WHO) prequalification for PNEUMOSIL®, containing CRM197 produced in Pelican Expression Technology

CRM197 News
01/07/2020
Photo of hands holding a vaccine with text

Ligand Licensee Begins Pivotal Phase 3 Study for Meningococcal ACWXY Conjugate Vaccine

PATH
09/01/2019
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Increased CRM197 Sales in Q1 2019

CRM197 News
05/14/2019
Pfenex case study titled

Ligand CRM197 is More Immunogenic than KLH in Mice

Ligand Case Study
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Ligand Licensee Succesfully Completes a Phase 3 Study and Enters Registration for Pneumosil®

CRM197 News
03/06/2019
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Milestone From Merck Associated With Clinical Advancement of Investigational 15-valent Pneumococcal Vaccine PCV-15 (V114)

CRM197 News
07/12/2018
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Analytical Assessment Shows Ligand (formerly Pfenex) CRM197 has Highest Purity

ScienceDirect.com | By: John M. Hickey, et al.
07/01/2018

Cross Reactive Material 197 glycoconjugate vaccines contain privileged conjugation sites

Nature Journal
02/04/2016
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Dedicated Facility Injects CRM197 Into Conjugate Vaccine Market

in-Pharma Technologist | By: Dan Stanton
01/21/2013
Logo for GEN: Genetic Engineering & Biotechnology News

Ligand Partner Begins Product Capacity Expansion

Genetic Engineering & Biotechnology News
01/16/2013
Photo of case study titled

Comparable Immunogenicity Observed in Peptides Coupled to Ligand CRM197 and KLH in a Mouse Model

Ligand Case Study
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Recombinant Production of Carrier Proteins

Genetic Engineering & Biotechnology News
12/01/2012

Carrier Protein Outsourcing

BioProcess International | Cassidy Brady, Kevin Killeen, William Taylor and Anant Patkar
11/01/2012
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Submission of Biologics Master File for Recombinant CRM197 to US FDA Announced

CRM197 News
05/17/2011
Pelican Expression Technology logo

Clinical Supply Agreement With Heny M. Jackson Foundation for the Advancement of Military Medicine Established

CRM197 News
11/30/2010

Events